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Clinical Trials News

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121-135 of 4127 results
Merck’s trial of inactivated varicella zoster virus vaccine meets primary end point
By PBR Staff Writer
Merck’s inactivated varicella zoster virus vaccine (VZV), V212, has met its primary endpoint in the first phase III study.
Contract Research & Services > Clinical Trials > News
Cyclacel's leukemia drug for elderly patients fails in phase 3 trial
By PBR Staff Writer
Cyclacel Pharmaceuticals’ leukemia drug for elderly patients failed to meet its primary endpoint in a phase 3 study.
Contract Research & Services > Clinical Trials > News
ProMetic’s pulmonary fibrosis drug yields positive results in phase 2 trial
ProMetic Life Sciences has revealed positive results for PBI-4050 from its open label Phase 2 clinical trial in idiopathic pulmonary fibrosis ("IPF") patients.
Contract Research & Services > Clinical Trials > News
GSK, Innoviva’s Relvar Ellipta shows positive effect in non-inferiority lung function study
By PBR Staff Writer
GlaxoSmithKline (GSK) and Innoviva’s non-inferiority lung function study of Relvar Ellipta has showed positive effect in patients with well-controlled asthma.
Contract Research & Services > Clinical Trials > News
ImmusanT’s phase 1b trial of celiac disease vaccine finds phase 2 dose regimen
ImmusanT has completed a phase 1b clinical trial evaluating the safety and tolerability of Nexvax2 in celiac disease.
Contract Research & Services > Clinical Trials > News
Argos' cancer treatment study recommended to be discontinued for futility
By PBR Staff Writer
An independent data monitoring committee (IDMC) has recommended Argos Therapeutics to halt the clinical trial of rocapuldencel-T cancer vaccine candidate, as it is unlikely to meet the primary endpoint.
Contract Research & Services > Clinical Trials > News
hVIVO says US body begins trial on malaria and Zika vaccine
Biopharmaceutical firm hVIVO PLC on Tuesday said the US National Institute of Health has initiated a phase one clinical trial of AGS-v, an investigational vaccine for mosquito-borne diseases like malaria and Zika.
Contract Research & Services > Clinical Trials > News
Chi-Med starts phase II study of savolitinib in pulmonary sarcomatoid carcinoma
Hutchison China MediTech has commenced a phase 2 study of savolitinib in locally advanced or metastatic pulmonary sarcomatoid carcinoma (PSC) in China.
Contract Research & Services > Clinical Trials > News
Faron Pharmaceuticals recruits first patient for new Traumakine trial
By PBR Staff Writer
Faron Pharmaceuticals has recruited its first patient to a phase II clinical trial of its lead drug, Traumakine, in the treatment of organ failure after a ruptured abdominal aorta aneurysm (RAAA).
Contract Research & Services > Clinical Trials > News
Daiichi Sankyo, ArQule’s tivantinib fails to meet primary end point in liver cancer study
By PBR Staff Writer
Daiichi Sankyo and ArQule announced that the tivantinib has failed to meet its primary endpoint in a phase 3 liver cancer study.
Contract Research & Services > Clinical Trials > News
AstraZeneca's Lynparza meets primary endpoint in breast cancer study
By PBR Staff Writer
A phase 3 study of AstraZeneca’s Lynparza (olaparib) met primary endpoint in a phase III trial in BRCA-mutated metastatic breast cancer.
Contract Research & Services > Clinical Trials > News
Pfizer's Xeljanz goes head-to-head with AbbVie's Humira in RA study
By PBR Staff Writer
Pfizer said its rheumatoid arthritis drug, Xeljanz, met primary endpoint in combination with methotrexate as compared to AbbVie's drug Humira, although it did not meet the primary endpoint on its own.
Contract Research & Services > Clinical Trials > News
Ardelyx's tenapanor shows significant effect in hyperphosphatemia in phase 3 trial
By PBR Staff Writer
A phase 3 trial evaluating Ardelyx's tenapanor, a novel treatment for hyperphosphatemia in patients with end-stage renal disease (ESRD) on dialysis, met its primary endpoint of significant difference in serum phosphorus levels.
Contract Research & Services > Clinical Trials > News
ViiV Healthcare unveils positive study results for two-drug regimen for HIV
ViiV Healthcare has announced positive results from its phase 3 program assessing the safety and efficacy of switching virologically suppressed patients from a three- or four-drug antiretroviral regimen to a two-drug regimen of dolutegravir and rilpivirine.
Contract Research & Services > Clinical Trials > News
Merck halts clinical trial of Alzheimer's drug
By PBR Staff Writer
Merck said it will halt a phase 2/3 clinical study of an experimental Alzheimer’s drug due to lack of efficacy.
Contract Research & Services > Clinical Trials > News
121-135 of 4127 results