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Clinical Trials News

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106-120 of 4175 results
Neurocrine’s Ingrezza fails in phase II Tourette syndrome study
Neurocrine Biosciences said that the initial phase II Tourette syndrome T-Force GREEN study of INGREZZA (valbenazine), a small molecule VMAT2 inhibitor, did not meet its primary endpoint.
Contract Research & Services > Clinical Trials > News
Inovio’s HIV vaccine succeeds in early stage trial
Inovio Pharmaceuticals' Pennvax-GP HIV vaccine has demonstrated nearly 100% immune response rates in a clinical study.
Contract Research & Services > Clinical Trials > News
FDA places clinical hold on Concert Pharmaceuticals’ hair loss drug
The US Food and Drug Administration (FDA) has placed a clinical hold on Concert Pharmaceuticals’ CTP-543 Phase 2a clinical trial for alopecia areata.
Contract Research & Services > Clinical Trials > News
Shire’s swelling disorder drug meets primary and secondary endpoints in phase 3 study
By PBR Staff Writer
Shire’s swelling disorder treatment, lanadelumab, has met its primary endpoint and all secondary endpoints in a phase 3 study.
Contract Research & Services > Clinical Trials > News
ImmunoGen unveils promising data with mirvetuximab soravtansine in ovarian cancer
ImmunoGen has reported promising safety and efficacy data from monotherapy and combination trials with mirvetuximab soravtansine in patients with folate receptor alpha (FRα)-positive epithelial ovarian cancer (EOC).
Contract Research & Services > Clinical Trials > News
Aduro Biotech expands clinical collaboration with Merck
Aduro Biotech has expanded its clinical collaboration with Merck to include an additional Phase 2 clinical trial.
Contract Research & Services > Clinical Trials > News
Summit completes patient enrollment in phase 2 trial of ezutromid in DMD
Summit Therapeutics has completed enrolment in PhaseOut DMD, a phase 2 proof of concept clinical trial of ezutromid, in Duchenne muscular dystrophy (DMD) patients.
Contract Research & Services > Clinical Trials > News
Ardelyx reports positive results from phase 3 trial of Tenapanor in IBS-C patients
Ardelyx reported positive, topline results from the T3MPO-1 trial, the first of two Phase 3 trials evaluating tenapanor for the treatment of patients with irritable bowel syndrome with constipation (IBS-C).
Contract Research & Services > Clinical Trials > News
Lilly’s migraine drug galcanezumab succeeds in three phase 3 studies
Eli Lilly's galcanezumab has met its primary endpoint in three phase 3 studies (EVOLVE-1, EVOLVE-2 and REGAIN) showing statistically significant reductions in the number of monthly migraine headache days against placebo at both studied doses.
Contract Research & Services > Clinical Trials > News
AstraZeneca’s Imfinzi meets primary endpoint in phase 3 NSCLC trial
By PBR Staff Writer
AstraZeneca’s Imfinzi (durvalumab) has significantly reduced the risk of disease worsening or death in patients with third stage lung cancer in a phase 3 trial.
Contract Research & Services > Clinical Trials > News
Roche’s advanced bladder cancer drug Tecentriq fails in phase 3 trial
Roche’s phase III IMvigor211 study of Tecentriq (atezolizumab) in people with locally advanced or metastatic urothelial cancer (mUC) whose disease progressed during or after treatment with a platinum-based chemotherapy (previously treated) has failed to meet its primary endpoint of overall survival (OS) compared to chemotherapy.
Contract Research & Services > Clinical Trials > News
Array, Merck to evaluate binimetinib-Keytruda combination for colorectal cancer
Array BioPharma and Merck have entered into a clinical trial collaboration agreement to investigate the safety and efficacy of the former’s MEK inhibitor, binimetinib, with Merck's anti-PD-1 therapy, Keytruda (pembrolizumab), in metastatic colorectal cancer patients with microsatellite stable tumors (MSS CRC).
Contract Research & Services > Clinical Trials > News
Daiichi Sankyo initiates phase 3b study of Lixiana
Daiichi Sankyo announced the initiation of the ENVISAGE-TAVI AF study of Lixiana by enrolling the first patient in the trial.
Contract Research & Services > Clinical Trials > News
Myovant’s hormonal therapy relugolix succeeds in phase 2 trial
Myovant Sciences has reported positive results from a placebo-controlled Phase 2 dose-finding trial evaluating the ability of relugolix to decrease heavy menstrual bleeding in women with uterine fibroids which was conducted by Takeda Pharmaceutical in Japan.
Contract Research & Services > Clinical Trials > News
Relvar Ellipta improves asthma control in Salford Lung Study
GlaxoSmithKline and Innoviva said that their asthma drug Relvar Ellipta yielded positive results from the Salford Lung Study (SLS) in 4,233 asthma patients treated by their own general practitioner in everyday clinical practice.
Contract Research & Services > Clinical Trials > News
106-120 of 4175 results