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Clinical Trials News

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ObsEva completes phase 1 first-in-women study of OBE022 to treat preterm labor
ObsEva has completed a Phase 1 single and multiple ascending dose study of OBE022, a potential first-in-class, once daily, oral and selective prostaglandin F2α, or PGF2α, receptor antagonist for the treatment of preterm labor in weeks 24 to 34 of pregnancy.
Contract Research & Services > Clinical Trials > News
Sunovion’s dasotraline improves ADHD symptoms in children in phase 2/3 study
By PBR Staff Writer
Sunovion Pharmaceuticals’ novel drug candidate dasotraline has demonstrated significantly improved attention deficit hyperactivity disorder (ADHD) symptoms in children compared to placebo in a phase 2/3 study.
Contract Research & Services > Clinical Trials > News
Novartis to commence phase 2 trial with bimagrumab in obese patients with type 2 diabetes
MorphoSys said its partner Novartis will conduct a phase 2 clinical trial of the HuCAL antibody bimagrumab in obese patients having type 2 diabetes.
Contract Research & Services > Clinical Trials > News
Visterra doses first patient in phase 2a trial of influenza A candidate VIS410
Visterra has dosed the first patient in the VIS410 Phase 2a clinical trial to study the monoclonal antibody for the treatment of hospitalized patients with influenza A, irrespective of the viral strain.
Contract Research & Services > Clinical Trials > News
ValiRX’s prostate cancer drug VAL201 shows positive results in Phase l/II trial
By PBR Staff Writer
ValiRx is extending its early stage trial of a prostate cancer drug, VAL201, after demonstrating disease stabilization, with a lower dose than was predicted by its preclinical evaluations.
Contract Research & Services > Clinical Trials > News
Debiopharm unveils positive phase 2 trial with Debio 1450 in ABSSSI patients
Debiopharm International has unveiled positive results from a large Phase II study of the staphylococcal-selective antibiotic Debio 1450 for the treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSI).
Contract Research & Services > Clinical Trials > News
Pfizer’s Humira biosimilar shows positive top line results
By PBR Staff Writer
Results from a Reflections B538-02 study with Pfizer’s investigational Humira (adalimumab) biosimilar, PF-06410293, demonstrated that the drug met its primary endpoint, and showed same efficacy to its reference product.
Contract Research & Services > Clinical Trials > News
Seattle Genetics starts phase 1 trial of SGN-CD352A in relapsed or refractory multiple myeloma
Seattle Genetics has enrolled the first patient in a multicenter phase 1 clinical trial of SGN-CD352A for patients with relapsed or refractory multiple myeloma (MM).
Contract Research & Services > Clinical Trials > News
Ionis’ type 2 diabetes candidate shows positive results in phase 2 study
Ionis Pharmaceuticals has reported positive data from phase 2 study of IONIS-GCGR Rx in patients with type 2 diabetes.
Contract Research & Services > Clinical Trials > News
Sun Pharma’s dry eye drug Seciera demonstrates positive results in phase 3 trial
By PBR Staff Writer
Sun Pharma’s drug Seciera, indicated for the treatment of dry eye disease, has demonstrated positive results in a 12-week multicentre phase-3 clinical trial.
Contract Research & Services > Clinical Trials > News
NewVac’s ovarian cancer combination meets primary endpoints in phase II trial
NewVac has met all primary endpoints in the Phase II Clinical Trial of Quisinostat, novel selective oral histone deacetylase (HDAC1) inhibitor, which the company licensed from Janssen Pharmaceutica.
Contract Research & Services > Clinical Trials > News
Zynerba starts phase 2 trial of ZYN002 in Fragile X syndrome
By PBR Staff Writer
Zynerba Pharmaceuticals has started an exploratory phase 2 clinical trial of ZYN002 cannabidiol (CBD) topical gel in children with Fragile X syndrome, genetic disorder that causes intellectual disability, behavioral and learning challenges.
Contract Research & Services > Clinical Trials > News
Incyte treats first patient in clinical trial program for ruxolitinib in GVHD
By PBR Staff Writer
Incyte has treated first patient in the clinical trial program of ruxolitinib (Jakafi) for the treatment of steroid-refractory acute graft-versus-host disease (GVHD).
Contract Research & Services > Clinical Trials > News
Alexion’s eculizumab fails to meet primary endpoint in phase 2/3 trial
Alexion Pharmaceuticals has reported results from the PROTECT Study, a Phase 2/3 registration trial of eculizumab (Soliris) for the prevention of delayed graft function (DGF) after kidney transplantation in adult recipients of a deceased donor kidney.
Contract Research & Services > Clinical Trials > News
Roche's emicizumab haemophilia drug succeeds in phase III trial
By PBR Staff Writer
A phase 3 clinical trial assessing Roche's emicizumab haemophilia drug in patients 12 years old and older met its primary endpoint.
Contract Research & Services > Clinical Trials > News
106-120 of 4068 results