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FDA places clinical hold on Regeneron and Teva’s pain drug trial
The US Food and Drug Administration (FDA) has placed a clinical hold on a phase 2b clinical trial evaluating fasinumab for the treatment of chronic low back pain over safety concerns.
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Clementia unveils results from phase 2 trial of palovarotene to treat FOP patients
Clementia Pharmaceuticals has announced top-line results from its Phase 2 clinical trial investigating palovarotene for the treatment of fibrodysplasia ossificans progressiva (FOP).
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Tetraphase doses first patient in phase 3 trial of Eravacycline in cIAI
Tetraphase Pharmaceuticals has dosed the first patient in IGNITE4, it's phase 3 clinical trial evaluating the efficacy and safety of intravenous (IV) eravacycline compared to meropenem in complicated intra-abdominal infections (cIAI).
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UK MHRA approves continued enrollment in BioMarin’s phase 1/2 study of BMN 270
The UK’s Medicines and Healthcare Products Regulatory Agency (MHRA) has approved continued enrollment in BioMarin Pharmaceutical’s phase 1/2 study of BMN 270 to treat severe hemophilia A.
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Trevi Therapeutics unveils positive results from phase 2 trial in prurigo nodularis
Trevi Therapeutics, which is developing oral Nalbuphine®ER for chronic pruritus conditions, announced positive results from its phase 2 trial for the treatment of moderate to severe prurigo nodularis.
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ProMetic's PBI-4050 significantly reduces liver fibrosis in alström syndrome patients
ProMetic Life Sciences announced that the Drug Safety Monitoring Board (DSMB) recommended that patient enrollment should continue in its ongoing Alström syndrome phase 2 clinical trial.
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BIOCAD Biotechnology begins phase 2 clinical trials of psoriasis drug
BIOCAD Biotechnology has started phase 2 clinical trials of a drug to treat severe psoriasis.
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Nymox unveils successful phase 3 long-term fexapotide repeat injection BPH trial results
Nymox Pharmaceutical has reported successful new study results from the long-term repeated injection group from the US Phase 3 trials for fexapotide, the Company's lead compound in late stage development for enlarged prostate (BPH) and for localized prostate cancer.
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Pfizer's drug improves survival in kidney cancer study
Pfizer has unveiled results from the Phase 3 S-TRAC clinical trial (Sunitinib Trial as Adjuvant Treatment of Renal Cancer) investigating SUTENT (sunitinib) as adjuvant therapy.
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Transgene partners with Merck, Pfizer for head and neck cancer trial
French gene therapy firm Transgene has partnered with Merck and Pfizer to evaluate a potential new combination treatment for head and neck cancer.
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Aprea enrolls first patients in phase II study of APR-246 to treat high-grade serous ovarian cancer
Aprea Therapeutics AB has enrolled the first patients in the Phase II part of the ongoing clinical study of APR-246 for the treatment of high-grade serous ovarian cancer.
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Scancell intends to develop SCIB2 for treatment of lung cancer
By PBR Staff Writer
Cancer immunotherapies developer Scancell said it intends to develop its SCIB2 ImmunoBody for the treatment of non-small-cell lung cancer and is preparing clinical trials in line with this goal.
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Exelixis unveils phase 1 trial results for cabozantinib in combination with nivolumab in advanced genitourinary tumors
Biopharmaceutical firm Exelixis has announced results from a phase 1 trial of cabozantinib in combination with nivolumab in patients with previously treated genitourinary tumors.
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Kite Pharma starts phase 1b/2 combination study for KTE-C19 and atezolizumab in refractory DLBCL
Kite Pharma has enrolled first patient in ZUMA-6, a phase 1b/2 clinical study of KTE-C19 in combination with atezolizumab, Genentech's anti-PD-L1 cancer immunotherapy.
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FDA accepts Velicept's IND to start phase I study for solabegron
The US Food and Drug Administration (FDA) has accepted Velicept Therapeutics' Investigational New Drug (IND) application to initiate a Phase I pharmacokinetic study for a once-daily formulation for solabegron.
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