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Pfizer's Herceptin biosimilar succeeds in breast cancer study
By PBR Staff Writer
A clinical trial comparing the safety and efficacy of Pfizer's biosimilar PF-05280014 to Roche's Herceptin met the primary endpoint in a breast cancer trial.
Contract Research & Services > Clinical Trials > News
Recro Pharma's IV meloxicam meets primary endpoint in phase 3 trial
Recro Pharma has unveiled positive results from its second of two Phase III clinical trials assessing intravenous (IV) meloxicam for the treatment of acute postoperative pain.
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GSK starts phase III studies of daprodustat for anaemia
By PBR Staff Writer
GlaxoSmithKline (GSK) has started phase III development program with daprodustat for anaemia associated with chronic kidney disease.
Contract Research & Services > Clinical Trials > News
Bavarian completes enrollment of phase 3 non-inferiority study of IMVAMUNE smallpox vaccine
Bavarian Nordic has completed enrollment of a Phase 3 clinical study designed to demonstrate non-inferiority between its investigational, non-replicating smallpox vaccine, IMVAMUNE and ACAM2000, the current U.S. licensed, and replicating smallpox vaccine.
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Juno Therapeutics places leukemia drug trial on clinical hold
Juno Therapeutics has voluntarily placed on hold the Phase II clinical trial of JCAR015 in adult patients with relapsed or refractory B cell acute lymphoblastic leukemia, known as the “ROCKET” trial.
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GSK's EGPA treatment meets endpoints in phase lll study
By PBR Staff Writer
A phase lll study of GlaxoSmithKline's mepolizumab has met its co-primary endpoints and all secondary endpoints in patients with eosinophilic granulomatosis with polyangiitis (EGPA).
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Eli Lilly’s Alzheimer's drug fails in phase 3 trial
Eli Lilly and Company said that its solanezumab monoclonal antibody designed to treat dimentia associated with Alzheimer’s disease (AD) did not meet its primary endpoint in a phase 3 study.
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FDA lifts partial clinical hold on AstraZeneca head and neck cancer trials
By PBR Staff Writer
AstraZeneca has restarted recruiting patients into two large clinical trials on head and neck cancer that had been paused over bleeding concerns.
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Diurnal doses first patient in native oral testosterone formulation phase I trial
Diurnal Group has dosed the first patient in its native oral testosterone formulation (DITEST) Phase I clinical trial.
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Stealth BioTherapeutics’ elamipretide infusion improves kidney microvasculature in phase 2 trial
By PBR Staff Writer
A single dose of Stealth BioTherapeutics’ elamipretide drug prior to renal artery angioplasty and stenting procedures enhanced kidney function and blood flow for three months post-procedure in a phase 2 clinical trial.
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BioSpecifics says phase 2b study of CCH succeeds in patients with cellulite
By PBR Staff Writer
BioSpecifics Technologies has unveiled positive, highly statistically significant results from a phase 2b study of collagenase clostridium histolyticum (CCH) to treat cellulite, or edematous fibrosclerotic panniculopathy.
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Janssen, GSK’s RA treatment sirukumab demonstrates mixed results against AbbVie’s Humira
By PBR Staff Writer
Johnson & Johnson’s experimental sirukumab treatment for rheumatoid arthritis (RA) demonstrated mixed results against AbbVie’s Humira in a large trial.
Contract Research & Services > Clinical Trials > News
Summit Therapeutics enrols first US patients in ezutromid trial for DMD
Summit Therapeutics has enrolled its first patients at trial sites in the US into PhaseOut DMD, a Phase 2 proof of concept clinical trial of ezutromid in patients with DMD.
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Amgen’s erenumab succeeds in second phase 3 migraine study
By PBR Staff Writer
Amgen said its migraine treatment met the primary endpoint of reducing monthly migraine days in patients with episodic migraine in a second phase 3 study.
Contract Research & Services > Clinical Trials > News
Janssen’s Guselkumab found safe for treatment of psoriatic arthritis in phase 2 study
A phase 2 study assessing Janssen Research & Development’s guselkumab has shown promise in the treatment of active psoriatic arthritis.
Contract Research & Services > Clinical Trials > News
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