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Clinical Trials News

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16-30 of 4175 results
Tricida begins phase 3 study of TRC101 to treat metabolic acidosis associated with chronic kidney disease
Tricida announced that the first subject was enrolled in TRCA-301, a phase 3 study evaluating TRC101 in chronic kidney disease (CKD) patients with metabolic acidosis.
Contract Research & Services > Clinical Trials > News
MD Anderson Cancer Center, Pfizer Oncology partner to assess immuno-oncology combinations in blood cancers and solid tumors
The University of Texas MD Anderson Cancer Center and Pfizer have entered into a clinical collaboration to study novel combinations of three Pfizer investigational immuno-oncology therapies and other Pfizer agents in the treatment of various solid tumors and hematologic malignancies.
Contract Research & Services > Clinical Trials > News
Immune’s bertilimumab yields positive results in phase 2 bullous pemphigoid trial
By PBR Staff Writer
Immune Pharmaceuticals has reported that its ongoing phase 2 trial of bertilimumab in patients with moderate to severe bullous pemphigoid (BP) has yielded positive results.
Contract Research & Services > Clinical Trials > News
Bevespi Aerosphere demonstrates statistically significant improvement in lung function in patients with COPD
AstraZeneca has announced positive top-line results of the Phase III, PINNACLE 4 trial in which Bevespi Aerosphere (glycopyrronium and formoterol fumarate 14.4/9.6 µg) demonstrated a statistically significant improvement in lung function in patients with chronic obstructive pulmonary disease (COPD).
Contract Research & Services > Clinical Trials > News
Axovant’s Alzheimer's drug intepirdine fails in phase 3 trial
By PBR Staff Writer
Axovant Sciences has reported that intepirdine, its 5-ht6 antagonist to treat Alzheimer's disease (AD), failed to meet its co-primary efficacy endpoints in a phase 3 trial.
Contract Research & Services > Clinical Trials > News
NewLink Genetics announces clinical collaboration to assess IO-based combination therapies in pancreatic cancer
NewLink Genetics announced that it has entered into a clinical collaboration agreement with AstraZeneca to evaluate the combination of indoximod, NewLink Genetics’ small molecule IDO pathway inhibitor, and durvalumab, AstraZeneca’s anti-PD-L1 monoclonal antibody, along with standard of care chemotherapy for patients with metastatic pancreatic cancer.
Contract Research & Services > Clinical Trials > News
Pfizer spins off new company with four rare disease therapies
By PBR Staff Writer
US pharma giant Pfizer has spun off four investigational drugs into a new medicines company, dubbed SpringWorks Therapeutics.
Contract Research & Services > Clinical Trials > News
Eleven Biotherapeutics completes Vicinium manufacturing for ongoing clinical trials in non-muscle invasive bladder cancer
Eleven Biotherapeutics announced that it has completed the manufacturing of all Vicinium necessary for its ongoing Phase 3 registration trial in patients with non-muscle invasive bladder cancer (NMIBC), and for its cooperative research and development agreement (CRADA) with the National Cancer Institute.
Contract Research & Services > Clinical Trials > News
AbbVie, Bristol-Myers to evaluate ABBV-399/Opdivo regimen in advanced solid tumors
By PBR Staff Writer
AbbVie will evaluate its investigational antibody drug conjugate, ABBV-399 (telisotuzumab vedotin), in combination with Bristol-Myers Squibb’s immunotheraphy Opdivo (nivolumab) in c-Met overexpressing non-small cell lung cancer (NSCLC).
Contract Research & Services > Clinical Trials > News
Versartis’ phase 3 Velocity trial of somavaratan in pediatric growth hormone deficiency did not meet primary endpoint
Versartis, an endocrine-focused biopharmaceutical firm that is developing somavaratan, a novel,aong-acting form of recombinant human growth hormone (rhGH) for growth hormone deficiency (GHD), announced that the Velocity Phase 3 clinical trial of somavaratan in pediatric growth hormone deficiency (GHD) did not meet its primary endpoint of non-inferiority.
Contract Research & Services > Clinical Trials > News
Cavion recruits first patient in multi-center phase 2 clinical trial in Essential Tremor
Cavion announced that the first patient has been enrolled in its new T-CALM Study (Tremor Cav3 Modulation Study), a Phase 2 clinical trial using the company’s T-type calcium channel modulator CX-8998 for patients with Essential Tremor (ET).
Contract Research & Services > Clinical Trials > News
Roche says Venetoclax combination improves PFS in phase III CLL trial
By PBR Staff Writer
Roche has reported that its cancer drug Venclexta/Venclyxto (venetoclax), developed jointly with AbbVie, has succeeded in a phase 3 study in chronic lymphocytic leukaemia (CLL) patients by meeting its primary endpoint.
Contract Research & Services > Clinical Trials > News
Bydureon EXSCEL trial shows favorable cardiovascular safety profile in patients with type-2 diabetes
AstraZeneca has announced full results from the EXSCEL (EXenatide Study of Cardiovascular Event Lowering) trial that showed cardiovascular safety with Bydureon (exenatide extended-release) in patients with type-2 diabetes (T2D) at a wide range of CV risk.
Contract Research & Services > Clinical Trials > News
Vanda's tradipitant improves itch and disease severity in patients with atopic dermatitis
Vanda Pharmaceuticals announced results from an eight-week randomized phase II clinical study of tradipitant as a monotherapy in the treatment of chronic pruritus in patients with atopic dermatitis.
Contract Research & Services > Clinical Trials > News
Amicus Therapeutics’ skin disorder drug SD-101 fails in phase 3 trial
By PBR Staff Writer
Amicus Therapeutics’ skin disorder drug SD-101 has failed to meet the primary endpoints and secondary endpoints in a phase 3 Essence clinical study.
Contract Research & Services > Clinical Trials > News
16-30 of 4175 results