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AstraZeneca’s COPD drug Duaklir meets primary endpoints in phase III Amplify trial
By PBR Staff Writer
AstraZeneca’s Duaklir (aclidinium bromide/formoterol 400µg/12µg twice-daily) has met its primary endpoints in the Phase III Amplify trial of patients with chronic obstructive pulmonary disease (COPD).
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Roche’s lung cancer drug Alecensa shows significant effect in global phase III study
By PBR Staff Writer
Roche’s lung cancer drug Alecensa (alectinib) has showed significant effect in the phase III ALUR study.
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Midatech submits MTD201 CTA filing for first in human study in carcinoid cancer and acromegaly
Midatech Pharma has announced the submission of a clinical trial application (CTA) for a first in human study of its MTD201 programme in carcinoid cancer and acromegaly.
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Novartis multiple sclerosis drug Gilenya shows siginificant effect in phase III trial
By PBR Staff Writer
Novartis’ multiple sclerosis (MS) drug Gilenya (fingolimod) has demonstrated significant effect in the phase III Paradigms study.
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Otonomy’s Otividex fails to meet primary endpoint in phase 3 trial for Ménière's Disease
Otonomy has announced results for its AVERTS-1 Phase 3 clinical trial of Otividex in patients with Ménière’s disease.
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Merck cholesterol drug reduces heart risk by 9% in study
By PBR Staff Writer
Merck’s cardiovascular treatment anacetrapib has reduced the risk of major coronary events in the REVEAL study.
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Apellis’ APL-2 meets primary endpoint in phase 2 study in patients with geographic atrophy
Apellis Pharmaceuticals’ complement C3 inhibitor, APL-2, met its primary endpoint in phase 2 clinical trial conducted on patients with geographic atrophy (GA) associated with age-related macular degeneration (AMD).
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Cancer Research UK launches clinical trial to test new cancer drug
Cancer Research UK has launched a clinical study to evaluate a new cancer drug in patients with advanced solid tumours in four centres across the UK through its Centre for Drug Development.
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Ultragenyx’ Ace-ER fails in phase 3 GNE Myopathy trial
Ultragenyx Pharmaceutical’s phase 3 study evaluating aceneuramic acid extended release (Ace-ER) in patients with GNE Myopathy (GNEM) failed to meet primary endpoint of showing a statistically significant difference in the upper extremity muscle strength composite score compared to placebo.
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ViraCyte announces positive phase 2 trial results
ViraCyte has announced publication of positive data from a Phase 2 clinical trial evaluating its most advanced T-cell immunotherapy product, Viralym-M.
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Boehringer initiates phase 1 trials of Zealand’s analogs for obesity and diabetes
By PBR Staff Writer
Zealand Pharma says that its partner Boehringer Ingelheim has launched phase 1 clinical trials to assess glucagon/GLP-1 agonist and an amylin analog as new treatment options for obesity and diabetes.
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Pfizer-led consortium begins trial of metastatic breast cancer treatment palbociclib
By PBR Staff Writer
Pfizer, along with Alliance Foundation Trials (AFT) and six other international cancer research groups, has commenced a phase 3 clinical study to assess palbociclib (Ibrance) for the treatment of patients with metastatic breast cancer.
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Ovid Therapeutics recruits first patient in phase 1b/2a trial of TAK-935/OV935 in adults with rare epilepsies
Ovid Therapeutics announced it has randomized the first patient in its Phase 1b/2a clinical trial of TAK-935, also known as OV935, in collaboration with Takeda Pharmaceutical Company Limited.
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Novartis, MMV begin patient trial of antimalarial compound in Africa
By PBR Staff Writer
Novartis and Medicines for Malaria Venture (MMV) have started a patient trial of antimalarial compound, KAF156, in Africa.
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US DOD to commence new trial with Pluristem's PLX-R18 cell therapy against ARS
Pluristem Therapeutics stated that a pilot study of its PLX-R18 cell therapy will be initiated by the US Department of Defense’s (DOD) Armed Forces Radiobiology Research Institute (AFRRI), part of the Uniformed Services University of Health Sciences (USU).
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