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Clinical Trials News

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Daiichi Sankyo selects anti-HER3 monoclonal antibody Patritumab for I-SPY 2 trial in breast cancer
Daiichi Sankyo and QuantumLeap Healthcare Collaborative announced that a new treatment arm of the I-SPY2 TRIAL will include patritumab, an investigational anti-HER3 monoclonal antibody.
Contract Research & Services > Clinical Trials > News
Lexicon reports positive results in phase 2 dose-ranging study for Sotagliflozin in type 1 diabetes
Lexicon Pharmaceuticals said that the Phase 2 dose-ranging, inTandem4 clinical trial of dual SGLT1 and SGLT2 inhibitor sotagliflozin met its primary endpoint, showing a statistically significant reduction in A1C at 12 weeks in patients with type 1 diabetes.
Contract Research & Services > Clinical Trials > News
AstraZeneca’s Lynparza shows significant PFS benefit in ovarian cancer patients
By PBR Staff Writer
A phase III trial designed to evaluate the efficacy of AstraZeneca’s Lynparza (olaparib) tablets as maintenance treatment for women with BRCA-mutated metastatic ovarian cancer has demonstrated significant progression-free survival (PFS) benefit.
Contract Research & Services > Clinical Trials > News
Global Blood Therapeutics to start phase 3 study for GBT440 in sickle cell disease
By PBR Staff Writer
Global Blood Therapeutics (GBT) will start a phase 3 clinical trial in December for GBT440 in adults and adolescents with sickle cell disease (SCD).
Contract Research & Services > Clinical Trials > News
Merck’s Keytruda meets primary endpoint in urothelial cancer study
By PKBR Staff Writer
A phase 3 study evaluating the use of Merck’s Keytruda (pembrolizumab) immunotherapy in patients with previously treated advanced urothelial cancer, met the primary endpoint of overall survival (OS).
Contract Research & Services > Clinical Trials > News
Amgen's Xgeva matches zoledronic acid in phase 3 trial in multiple myeloma-related bone complications
By PBR Staff Writer
A phase 3 study assessing Amgen’s Xgeva (denosumab) compared to zoledronic acid (ZA) for the prevention of bone complications in newly diagnosed multiple myeloma (MM) patients met its primary endpoint.
Contract Research & Services > Clinical Trials > News
Sanifit starts first clinical trial of SNF472 in patients with calciphylaxis
Laboratoris Sanifit has started the first clinical trial of its lead candidate, SNF472, for the treatment of the orphan disease calciphylaxis (calcific uraemic arteriolopathy, CUA).
Contract Research & Services > Clinical Trials > News
Theravance and Mylan’s COPD treatment shows benefits in phase 3 trials
By PBR Staff Writer
A drug that is being developed by Theravance Biopharma and Mylan has shown promise in two phase 3 efficacy studies treating patients with chronic obstructive pulmonary disease.
Contract Research & Services > Clinical Trials > News
Merck's letermovir succeeds in preventing CMV infection in phase 3 study
A phase 3 clinical trial evaluating Merck's letermovir for prevention of cytomegalovirus (CMV) infection in high-risk bone marrow transplant patients, met its primary endpoint.
Contract Research & Services > Clinical Trials > News
Eiger doses first patient in phase 2 LIMT HDV study
Eiger BioPharmaceuticals has dosed the first patient in the Phase 2 LIMT HDV (Lambda Interferon MonoTherapy in HDV) study, a monotherapy trial of pegylated interferon lambda 1a (Lambda) as a potential treatment for chronic hepatitis D virus (HDV) infection.
Contract Research & Services > Clinical Trials > News
LLS launches collaborative clinical trial for acute myeloid leukemia
The Leukemia & Lymphoma Society (LLS) has launched a collaborative clinical trial for acute myeloid leukemia (AML), a deadly disease which has seen few improvements in treatments in over 40 years.
Contract Research & Services > Clinical Trials > News
FDA places clinical hold on Regeneron and Teva’s pain drug trial
The US Food and Drug Administration (FDA) has placed a clinical hold on a phase 2b clinical trial evaluating fasinumab for the treatment of chronic low back pain over safety concerns.
Contract Research & Services > Clinical Trials > News
Clementia unveils results from phase 2 trial of palovarotene to treat FOP patients
Clementia Pharmaceuticals has announced top-line results from its Phase 2 clinical trial investigating palovarotene for the treatment of fibrodysplasia ossificans progressiva (FOP).
Contract Research & Services > Clinical Trials > News
Tetraphase doses first patient in phase 3 trial of Eravacycline in cIAI
Tetraphase Pharmaceuticals has dosed the first patient in IGNITE4, it's phase 3 clinical trial evaluating the efficacy and safety of intravenous (IV) eravacycline compared to meropenem in complicated intra-abdominal infections (cIAI).
Contract Research & Services > Clinical Trials > News
UK MHRA approves continued enrollment in BioMarin’s phase 1/2 study of BMN 270
The UK’s Medicines and Healthcare Products Regulatory Agency (MHRA) has approved continued enrollment in BioMarin Pharmaceutical’s phase 1/2 study of BMN 270 to treat severe hemophilia A.
Contract Research & Services > Clinical Trials > News
136-150 of 4028 results