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Pfizer Phase III renal cell carcinoma study fails to meet primary endpoint
Pfizer has reported topline results from Phase III INTORSECT (B1771003) study of Torisel as second-line treatment in advanced renal cell carcinoma (RCC).
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Contract Research & Services > Clinical Trials > News
BioAlliance begins Phase III liver cancer study with Livatag
BioAlliance Pharma has begun ReLive, Phase III clinical trial with Livatag (doxorubicin Transdrug) in primary liver cancer patients.
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Contract Research & Services > Clinical Trials > News
Takeda Phase III Crohn's disease trial meets primary endpoints
Takeda Pharmaceutical Company has announced that GEMINI II pivotal Phase III trial of vedolizumab in moderately to severely active Crohn's disease patients has met primary endpoints.
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Contract Research & Services > Clinical Trials > News
Galapagos commences Phase IIa rheumatoid arthritis study
Galapagos has initiated Phase IIa clinical study designed to assess efficacy and safety of GLPG0634 in rheumatoid arthritis (RA) patients.
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Contract Research & Services > Clinical Trials > News
Seattle Genetics announces phase II clinical trial results for Adcetris
Biotechnology firm Seattle Genetics has announced the interim results from an investigator-sponsored phase II clinical trial of Adcetris (brentuximab vedotin) in patients with relapsed cutaneous T-cell lymphoma (CTCL).
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Contract Research & Services > Clinical Trials > News
Alnylam ALN-TTR01 drug shows efficacy in Phase I study
Alnylam Pharmaceuticals has reported results from the Phase I clinical trial with ALN-TTR01, an RNAi therapeutic targeting transthyretin (TTR) for the treatment of TTR-mediated amyloidosis (ATTR).
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Contract Research & Services > Clinical Trials > News
ISTA Pharma presents Prolensa Phase 3 clinical data
ISTA Pharmaceuticals has announced results from the second of two Phase 3 studies of its once-daily topical nonsteroidal anti-inflammatory (NSAID) product candidate Prolensa (bromfenac ophthalmic solution), used for treatment of ocular inflammation and pain following cataract surgery.
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Contract Research & Services > Clinical Trials > News
DSP announces positive results from Phase III trials with Latuda
Dainippon Sumitomo Pharma (DSP) has reported that Latuda has met the primary and secondary endpoints in two Phase III trials in Bipolar I Depression.
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Contract Research & Services > Clinical Trials > News
Millennium, Seattle Genetics commence Phase III CTCL trial
Millennium and Seattle Genetics have begun a randomized open-label Phase III trial, evaluating Adcetris (brentuximab vedotin) in patients with CD30-expressing cutaneous T-cell lymphoma (CTCL).
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Contract Research & Services > Clinical Trials > News
Genta initiates TESEGAST trial with tesetaxel in gastric cancer patients
Genta has dosed first patient with advanced gastric cancer in the new randomized double-blind, placebo-controlled trial of tesetaxel, known as TESEGAST.
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Contract Research & Services > Clinical Trials > News
Novartis reports positive results from Phase III study with pasireotide
Novartis has reported positive results from Phase III study which showed that Pasireotide (SOM230) long-acting release (LAR) was effective at inducing full biochemical control compared to Sandostatin LAR (octreotide/IM injection).
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Contract Research & Services > Clinical Trials > News
Generon commences Phase II breast cancer trial with F-627
Generon (Shanghai) Corporation has announced the commencement of the Phase II clinical trial of F-627 in women with breast cancer receiving myelotoxic chemotherapy.
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Contract Research & Services > Clinical Trials > News
Pfizer Phase III Lyrica study fails to meet primary efficacy endpoint
Pfizer has reported that Phase III randomized withdrawal design study for Lyrica (pregabalin) in painful diabetic peripheral neuropathy (pDPN) patients has failed to meet its primary efficacy endpoint.
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Contract Research & Services > Clinical Trials > News
Isis begins Phase II hypertriglyceridemia study with ISIS-APOCIIIRx
Isis Pharmaceuticals has begun the Phase II study evaluating the safety and efficacy of ISIS-APOCIIIRx in patients with very high triglycerides.
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Contract Research & Services > Clinical Trials > News
CSL Behring begins Phase I/II hereditary angioedema study
CSL Behring has begun Phase I/II study of subcutaneous administration of C1-esterase inhibitor in hereditary angioedema patients (HAE).
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Contract Research & Services > Clinical Trials > News