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Daiichi Sankyo, ArQule’s tivantinib fails to meet primary end point in liver cancer study
By PBR Staff Writer
Daiichi Sankyo and ArQule announced that the tivantinib has failed to meet its primary endpoint in a phase 3 liver cancer study.
Contract Research & Services > Clinical Trials > News
AstraZeneca's Lynparza meets primary endpoint in breast cancer study
By PBR Staff Writer
A phase 3 study of AstraZeneca’s Lynparza (olaparib) met primary endpoint in a phase III trial in BRCA-mutated metastatic breast cancer.
Contract Research & Services > Clinical Trials > News
Pfizer's Xeljanz goes head-to-head with AbbVie's Humira in RA study
By PBR Staff Writer
Pfizer said its rheumatoid arthritis drug, Xeljanz, met primary endpoint in combination with methotrexate as compared to AbbVie's drug Humira, although it did not meet the primary endpoint on its own.
Contract Research & Services > Clinical Trials > News
Ardelyx's tenapanor shows significant effect in hyperphosphatemia in phase 3 trial
By PBR Staff Writer
A phase 3 trial evaluating Ardelyx's tenapanor, a novel treatment for hyperphosphatemia in patients with end-stage renal disease (ESRD) on dialysis, met its primary endpoint of significant difference in serum phosphorus levels.
Contract Research & Services > Clinical Trials > News
Woodley Equipment Company Exhibit at Outsourcing in Clinical Trials West Coast 2017
The Clinical Trials Team at Woodley Equipment Company is exhibiting at Outsourcing in Clinical Trials West Coast 2017, which is taking place at the Hyatt Regency San Francisco Airport on Wednesday 22nd and Thursday 23rd February
Contract Research & Services > Clinical Trials > Press Releases
ViiV Healthcare unveils positive study results for two-drug regimen for HIV
ViiV Healthcare has announced positive results from its phase 3 program assessing the safety and efficacy of switching virologically suppressed patients from a three- or four-drug antiretroviral regimen to a two-drug regimen of dolutegravir and rilpivirine.
Contract Research & Services > Clinical Trials > News
Merck halts clinical trial of Alzheimer's drug
By PBR Staff Writer
Merck said it will halt a phase 2/3 clinical study of an experimental Alzheimer’s drug due to lack of efficacy.
Contract Research & Services > Clinical Trials > News
Axovant's nelotanserin demonstrates treatment benefit in phase 2 dementia study
By PBR Staff Writer
Axovant Sciences said its drug nelotanserin has passed an early hurdle in a phase 2 study for Lewy body dementia, encouraging it to start preparing for a phase 3 study.
Contract Research & Services > Clinical Trials > News
Tracon's lead product candidate fails in phase 2 study in brain cancer trial
Tracon Pharmaceuticals said that data from a phase 2 study demonstrated that a combination of its endoglin antibody TRC105 with Avastin (bevacizumab) did not perform significantly better than Avastin alone for progression-free survival in patients with recurrent glioblastoma.
Contract Research & Services > Clinical Trials > News
Immunomedics, Seattle Genetics sign $2bn licensing deal for cancer drug
By PBR Staff Writer
Immunomedics has signed a development and licensing agreement worth up to $2bn with Seattle Genetics for its experimental cancer drug.
Contract Research & Services > Clinical Trials > News
Jazz enrolls first patient in JZP-110’s phase 2 trial for excessive sleepiness in PD patients
Jazz Pharmaceuticals has enrolled its first patient for the Phase 2 clinical study of JZP-110, a selective dopamine and norepinephrine reuptake inhibitor, as a potential option for excessive sleepiness (ES) in adult patients with Parkinson's disease.
Contract Research & Services > Clinical Trials > News
Viking's VK2809 demonstrates positive effect in POC study in glycogen storage disease
Preliminary results from a proof-of-concept (POC) study evaluating Viking Therapeutics' VK2809 in an in vivo model of a rare orphan disorder, dubbed glycogen storage disease Ia (GSD 1a), demonstrated an encouraging effect.
Contract Research & Services > Clinical Trials > News
Male contraceptive gel succeds in monkey trials
By PBR Staff Writer
A new type of male contraceptive polymer hydrogel which works by blocking sperm in the vas deferens has been successful in monkey trials.
Contract Research & Services > Clinical Trials > News
GW Pharmaceuticals' Cannabis-derived drug shows promise in brain cancer trial
GW Pharmaceuticals has unveiled positive top-line results from an exploratory Phase 2 placebo-controlled clinical study of a combination of tetrahydrocannabinol (THC) and cannabidiol (CBD) in 21 patients with recurrent glioblastoma multiforme, or GBM.
Contract Research & Services > Clinical Trials > News
Immunovaccine’s immuno-oncology candidate to enter phase 2 trial in ovarian cancer
Immunovaccine has announced that the UHN’s Princess Margaret Cancer Centre (PM) will carry out a Phase 2 clinical trial to assess the use of a combination of immunotherapies from Immunovaccine and Merck.
Contract Research & Services > Clinical Trials > News

PBR Supplier Recommendations

CRFweb... from Clindox, Suppliers of Clinical Trial Software
CRFweb is the groundbreaking eCRF application brought to you by Clindox. It sets new standards in web-based, clinical trial software. The combination of a comprehensive feature set, incredibly quick set-up time, simplicity of use and flexible pricing means no trial is too large or too small to be practical. The whole process is genuinely DIY, allowing trial managers to really take control of their trial. ... Contract Research & Services > Clinical Trials > Suppliers
LABORATORIOS INIBSA - Pharmaceutical Contract Manufacturing Company
LABORATORIOS INIBSA is a pharmaceutical contract manufacturing company. We have more than 60 years' experience and belong to the INIBSA GROUP. INIBISA supplies products and services to Biotools, Inibsa Dental and Inibsa Hospital, as well as other pharmaceutical companies through our contract manufacturing division. From our facilities in Lliçà de Vall, 20km from Barcelona LABORATORIOS INIBSA currently supplies more than 50 countries worldwide.... Contract Research & Services > Clinical Trials > Suppliers
Vaisala - Supplier of Continuous Monitoring Systems for Controlled Life Science Environments
Vaisala is a world leader in environmental and industrial measurement systems and instrumentation. We offer measurement instrumentation, continuous monitoring systems and validation systems to measure and supervise environmental conditions, within regulated or controlled life science environments.... Contract Research & Services > Clinical Trials > Suppliers
Quintiles - Bringing People and Knowledge Together for a Healthier World
Quintiles applies the breadth and depth of our service offerings along with extensive therapeutic, scientific and analytics expertise to help our customers navigate an increasingly complex healthcare environment.... Contract Research & Services > Clinical Trials > Suppliers
CTL Laboratories - Contract Immune Monitoring and Research
Cellular Technology Limited (CTL) is a privately-held biotechnology company that is a global leader within the enzyme-linked immunosorbent spot (ELISPOT) field. Establishing the ELISPOT instrumentation and scientific principles over the past two decades has helped to define the parameters of ELISPOT research for the monitoring of cell-mediated immunity.... Contract Research & Services > Clinical Trials > Suppliers
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PBR White Paper Recommendations

Reliable, Long-range Wireless Sensors for Environmental Monitoring By Vaisala pbr
The Vaisala viewLinc Monitoring System tracks environmental conditions wirelessly using Vaisala’s VaiNet wireless devices based on LoRa™* technology. By using a chirp spread spectrum (CSS)* wireless protocol, VaiNet provides robust communication that is extremely reliable over long distances and under harsh, complex and obstructed conditions.... Contract Research & Services > Clinical Trials > White Papers Sciences Radiolabelling Brochure By Almac
Trust Almac with your 14C radiolabelling requirements and we will offer advice on the most appropriate label position for your molecule, including synthetic feasibility and metabolic stability.... Contract Research & Services > Clinical Trials > White Papers Commerical Packaging By Almac
- Complementary US and UK operations, - Quality-driven, flexible packaging solutions, - Market leader for product launch of niche / orphan drug products, - Solid oral dose and biopharmaceutical packaging, - Packaging and artwork design, - Full serialisation and 2D matrix barcoding solutions.... Contract Research & Services > Clinical Trials > White Papers Providing an Unparalleled Range of Contract Pharmaceutical Development and Manufacturing Services Globally for Over 40 Years By Almac
Only we can combine the expertise from our range of specialised services to provide you with the right solutions to help you develop and commercialise your products.... Contract Research & Services > Clinical Trials > White Papers Building the Next Generation IRT: An Exclusive Look Under the Hood of IXRS®3 By Almac
Interactive Response Technology (IRT) systems - used to manage patient interactions and drug supplies during clinical trials - perform a range of functions for sponsors, drug depots, and investigative sites. Yet, they are typically viewed by sponsors as a "painful necessity" rather than as a welcome, invaluable tool. That perception exists because the underlying technology is outmoded, and the user's experience is stuck in the pre-Internet era. While established systems are "tried and true" in that they have supported thousands of clinical trials over the years, they can also be tired and cumbersome.... Contract Research & Services > Clinical Trials > White Papers See more
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