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Clinical Trials

Novartis reports positive results from two Phase III trials of secukinumab in ankylosing spondylitis By PBR Staff Writer
Novartis has reported positive results from its Phase III trials MEASURE 1 and MEASURE 2 of its investigational medicine AIN457 (secukinumab) in patients with ankylosing spondylitis (AS).
Contract Research & Services > Clinical Trials > News
Boehringer starts Phase III colorectal cancer trial of nintedanib By PBR Staff Writer
Germany-based Boehringer Ingelheim has initiated patient enrollment in a new global Phase III trial called LUME-COLON 1 of nintedanib to treat advanced colorectal cancer (CRC).
Contract Research & Services > Clinical Trials > News Phosplatin starts dosing in Phase I trial of PT-112 for solid tumors By PBR Staff Writer
Phosplatin Therapeutics has dosed the first group of patients in its Phase I first-in-human clinical trial of PT-112, the lead therapeutic candidate among its phosphaplatin family of molecules, to treat solid tumors.
Contract Research & Services > Clinical Trials > News
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Global Capabilities in Central Nervous System Research
| By PRA Health Sciences
PRA Health Sciences’ (PRA) Early Development Services (EDS) group has a long-standing track record of early clinical development work in various CNS indications through our global clinical facilities.
Contract Research & Services > Clinical Trials > White Papers
Phosplatin starts dosing in Phase I trial of PT-112 for solid tumors
By PBR Staff Writer
Phosplatin Therapeutics has dosed the first group of patients in its Phase I first-in-human clinical trial of PT-112, the lead therapeutic candidate among its phosphaplatin family of molecules, to treat solid tumors.
Contract Research & Services > Clinical Trials > News
CEO of IPERION will speak at the ECA GMP Course March 2015
CEO Karel Bastiaanssen will give two presentations at the ECA GMP Course Cloud Computing and Outsourcing in a GxP Environment. The course will take place 12-13 March in Berlin, Germany, where the cloud service provider business and operating as a cloud service provider will be highlighted.
Contract Research & Services > Clinical Trials > Press Releases
Cystic Fibrosis: Pulmonary Aspects of the Disease
| By Cromsource
Cystic fibrosis (CF) is a genetic disease which is usually caused by the absence, dysfunction or reduced number of the multifunctional CF transmembrane regulator (CFTR) protein... Recently new therapy approaches such as ivacaftor have emerged which target the cause of the condition itself. This white paper focusses only on the current treatment of pulmonary complications of CF.
Contract Research & Services > Clinical Trials > White Papers
Genervon reports Phase IIa trial results of GM6 drug in ALS and PD
By PBR Staff Writer
Genervon Biopharmaceuticals has reported results from its two Phase IIa double blinded, randomized, placebo controlled clinical trials of its drug candidate GM6 in patients with Amyotrophic Lateral Sclerosis (ALS) and Parkinson’s disease (PD).
Contract Research & Services > Clinical Trials > News
Amicus Therapeutics reports positive phase III data from fabry monotherapy study 011
Amicus Therapeutics (FOLD), a biopharmaceutical company at the forefront of therapies for rare and orphan diseases, has announced additional positive data from a Phase 3 study (Study 011) of the oral small molecule chaperone migalastat HCl ("migalastat") in Fabry disease patients with amenable mutations.
Contract Research & Services > Clinical Trials > News
Sponsor and CRO Pharmacovigilance Alliances
| By PRA Health Sciences
Outsourcing pharmacovigilance activities is a standard business practice in a rapidly expanding market segment. In the past, outsourced safety services were limited due to concerns about confidentiality, data security and liability in cases of regulatory non-compliance, which are all still important considerations today.
Contract Research & Services > Clinical Trials > White Papers
Translating Cancer Genomics Into a Personalised Approach for Cancer Patients
| By PRA Health Sciences
This white paper provides a brief history of oncology genomics, including development, uses in improving patient care, current achievements and challenges and the future direction of cancer genomics.
Contract Research & Services > Clinical Trials > White Papers
EMA grants orphan drug status for Immunomedics' isactuzumab govitecan for pancreatic cancer
By PBR Staff Writer
The European Medicines Agency (EMA) has granted orphan drug status for Immunomedics' solid-tumor antibody-drug conjugates (ADCs), isactuzumab govitecan, or IMMU-132, to treat pancreatic cancer.
Contract Research & Services > Clinical Trials > News
Epizyme reports positive pre-clinical Phase I/II trial results of EPZ in synovial sarcoma
By PBR Staff Writer
Epizyme has reported positive pre-clinical data from its Phase I/II trial of EPZ-6438 (E7438), its oral, small molecule inhibitor of EZH2, in models of synovial sarcoma, a soft tissue sarcoma that typically affects young adults.
Contract Research & Services > Clinical Trials > News
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