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Clinical Trials

Reata enrolls first patient in Phase II/III MOXIe study of RTA 408 in friedreich's ataxia patients Reata announces enrollment of the first patient in a Phase 2 dose-ranging study examining the safety, tolerability, and efficacy of RTA 408 Oral Capsules versus placebo for the treatment of patients with Friedreich's ataxia.
Contract Research & Services > Clinical Trials > News
International Stem Cell to begin Phase I/IIa Parkinson's disease trial in Australia By PBR Staff Writer
US-based biotechnology firm International Stem Cell (ISCO) has completed the required preclinical studies and is planning to start the Phase I/IIa clinical trial of its clinical product ISC-hpNSC to treat Parkinson's disease in Australia within the next few months.
Contract Research & Services > Clinical Trials > News Novartis reports positive results from Jakavi Phase III trial in patients with polycythemia vera By PBR Staff Writer
Swiss drug-maker Novartis has reported positive results from its pivotal Phase III clinical trial of Jakavi (ruxolitinib), an oral inhibitor of the JAK 1 and JAK 2 tyrosine kinases, to treat patients with polycythemia vera (PV).
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Extending Soft Gelatin Capsule Benefits to Novel Fixed Dose Combinations: Unigel
Fixed dose combinations are desirable for several reasons such as different release profiles and guaranteeing patientsĀ“ compliance by reducing the daily intake of a drug product(s).
Contract Research & Services > Clinical Trials > Press Releases
Alexza begins Phase IIa trial of AZ-002 to treat epilepsy patients
By PBR Staff Writer
US-based Alexza Pharmaceuticals has started a Phase IIa trial of AZ-002 (Staccato alprazolam), which is being developed for the management of epilepsy in patients with acute repetitive seizures (ARS).
Contract Research & Services > Clinical Trials > News
ImmuPharma, Simbec-Orion collaborate to execute Phase III Lupuzor trial for Lupus
By PBR Staff Writer
ImmuPharma and Simbec-Orion have entered into a collaboration agreement to execute ImmuPharma's Phase III clinical trial of its lead compound Lupuzor to treat Lupus, a chronic, potentially life-threatening autoimmune disease.
Contract Research & Services > Clinical Trials > News
FDA clears Advaxis' IND application to conduct Phase I trial of ADXS-HER2
By PBR Staff Writer
The US Food and Drug Administration (FDA) has cleared Advaxis' investigational new drug (IND) application to conduct a Phase I clinical trial of ADXS-HER2 (ADXS31-164) to treat patients with metastatic HER2 expressing solid tumors.
Contract Research & Services > Clinical Trials > News
Kineta closes patient enrollment in Phase Ib trial of ShK-186 to treat psoriasis
By PBR Staff Writer
US-based biotechnology company Kineta has completed patient enrolment in its Phase Ib proof-of-concept clinical trial of its new, immune-sparing therapeutic, ShK-186, to treat psoriasis.
Contract Research & Services > Clinical Trials > News
Kinex doses first patient with KX2-391 ointment for actinic keratosis in Phase I trial
Kinex Pharmaceuticals announced today that the first actinic keratosis patient has been dosed with KX2-391 ointment in Austin, Texas.
Contract Research & Services > Clinical Trials > News
Minerva Neurosciences reports positive phase I data with MIN-202
Minerva Neurosciences, announced that preliminary results from a Phase 1 clinical study showed that treatment with MIN-202, a selective orexin-2 antagonist, resulted in significant improvements in sleep onset and sleep duration in patients with comorbid insomnia related to major depressive disorder (MDD).
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Ocular begins patient enrolment in dexamethasone Phase II trial for dry eye disease
By PBR Staff Writer
US-based biopharmaceutical firm Ocular Therapeutix has started patient enrolment in a Phase II clinical trial of sustained release dexamethasone (OTX-DP), an ophthalmic corticosteroid to treat inflammatory dry eye disease.
Contract Research & Services > Clinical Trials > News
AM-Pharma initiates Phase II trial of recAP in AKI patients
By PBR Staff Writer
AM-Pharma has started its Phase II trial of recombinant human Alkaline Phosphatase (recAP) to treat sepsis-associated acute kidney injury (AKI).
Contract Research & Services > Clinical Trials > News
Immunomedics reports phase I/II results of sacituzumab govitecan in gastrointestinal cancers patients
Immunomedics, announced that sacituzumab govitecan, the company's lead investigational antibody-drug conjugate (ADC), produces partial response (PR) in some patients with metastatic esophageal and colorectal cancers who had been heavily pretreated.
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