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NIH to provide funding for Alzheimer's advance clinical trials By PBR Staff Writer
US-based National Institutes of Health (NIH) is set to provide financial assistance to a new clinical trials consortium to enhance studies for therapies in Alzheimer’s disease and related dementias.
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Pfizer's breast cancer drug improves progression-free survival in Phase 3 trial Pfizer announced that talazoparib has improved progression-free survival (PFS) in patients with germline (inherited) BRCA1/2-positive (gBRCA+) locally advanced or metastatic breast cancer (MBC) in the Phase 3 Embraca study.
Contract Research & Services > Clinical Trials > News Lilly’s Cyramza meets primary endpoint in phase 3 gastric cancer trial By PBR Staff Writer
Eli Lilly and Company’s (Lilly) phase 3 trial of Cyramza (ramucirumab) for the treatment of a type of gastric cancer was a mixed bag as it met its primary objective of preventing the condition from advancing but could not improve overall survival (OS).
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Roche’s lung cancer drug combo study shows improvement in progression-free survival
By PBR Staff Writer
Roche has announced that the combination of Tecentriq (atezolizumab) and Avastin (bevacizumab) plus chemotherapy (carboplatin and paclitaxel) has extended the life of patients with previously untreated advanced non-squamous non-small cell lung cancer (NSCLC) in the Phase III IMpower150 study.
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Novartis' Kisqali improves PFS in younger women with advanced breast cancer
By PBR Staff Writer
Results from a phase 3 clinical trial evaluating Novartis' Kisqali (ribociclib) in premenopausal women with HR+/HER2- advanced/metastatic breast cancer demonstrated a significant treatment benefit.
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Janssen’s Imbruvica- rituximab combination meets primary end point in phase 3 study
By PBR Staff Writer
Janssen Research & Development (Janssen) has announced that the combination of Imbruvica (ibrutinib) and rituximab (Rituxan) has improved progression-free survival (PFS) in patients with Waldenstrom macroglobulinemia (WM) in the Phase 3 iNNOVATE (PCYC-1127) study.
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Realm Therapeutics doses first patient in phase 2 study of PR022 to treat atopic dermatitis
Realm Therapeutics announced that the first patient has been dosed in its Phase 2 study of PR022, the Company's proprietary topical gel formulation of high concentration hypochlorous acid, for the treatment of atopic dermatitis.
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AbbVie’s risankizumab meets all primary endpoints in fourth phase 3 psoriasis trial
By PBR Staff Writer
AbbVie’s psoriasis drug risankizumab (150 mg) has met all the primary endpoints in the two phases of a fourth pivotal phase 3 clinical trial in patients with moderate to severe plaque psoriasis.
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NIH and partners commence HIV vaccine efficacy trial
The National Institutes of Health (NIH) and partners have started a clinical trial to evaluate whether an experimental HIV vaccine regimen is safe and effective in prevention of HIV infection.
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Revance Therapeutics plans phase 3 program for RT002 injectable to treat cervical dystonia
Revance Therapeutics has completed its End-of-Phase 2 meeting with the US Food and Drug Administration (FDA) and has received scientific advice from the Europe Medicines Agency (EMA) regarding DaxibotulinumtoxinA for Injection (RT002) for the treatment of cervical dystonia.
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Novartis and Amgen’s erenumab succeeds in phase 3 episodic migraine trial
By PBR Staff Writer
Novartis and Amgen’s human monoclonal antibody erenumab has succeeded in a phase 3 study by demonstrating significant and sustained efficacy in the prevention of episodic migraine.
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Viking’s VK5211 meets primary endpoint in phase 2 hip fracture trial
By PBR Staff Writer
Viking Therapeutics’ hip fracture treatment VK5211 has met primary endpoint in a 12-week phase 2 clinical trial.
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Takeda starts phase 1 trial of Zika virus vaccine candidate
By PBR Staff Writer
Japan's Takeda Pharmaceutical has started a phase 1 clinical trial of its purified, inactivated, alum-adjuvanted, whole Zika virus vaccine candidate, TAK-426.
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